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README.txt (5.03 kB)
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Ingenuity Pathway Analyses.zip (3.61 MB)
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Figures.zip (1.31 MB)
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Expression Counts.zip (1.92 MB)
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Comparisons.zip (2.98 MB)
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Cell Preparation Protocols.zip (223.22 kB)
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Comparison of type 1 conventional dendritic cells pre-cDC1 and CD8+ cDC1 and dendritic cells from bendamustine- or cyclophosphamide-treated mice
Dendritic cells (DCs) harvested from murine spleens to evaluate the effect of treatment with two chemotherapeutic agents: bendamustine and cyclophosphamide. Previous work found that bendamustine treatment results in accumulation of the type 1 conventional DC precursor (pre-cDC1). Pre-cDC1 are an understudied population of murine DCs. This 2x2 study compared the transcriptional profile of bendamustine versus cyclophosphamide and pre-cDC1 versus the mature CD8+ cDC1.
For inquiries regarding the contents of this dataset, please contact the Corresponding Author listed in the README.txt file. Administrative inquiries (e.g., removal requests, trouble downloading, etc.) can be directed to data-management@arizona.edu
